Acanthosis Nigricans - Causes, Symptoms and Treatment
Acanthosis
nigricans is a fell disorder characterized by dark, thick, velvety skin
in body folds and creases, caused by too much insulin in the blood.
High insulin inches in the blood can lead to diabetes and other chronic
health problems such as obesity, high blood pressure, and heart
problems. It can occur with endocrine diseases such as Cushing disease ,
tumors of the pituitary , and diabetes mellitus.
It is
usually setialed into 2 types: a benign form and a malignant form. The
most common fatality associated with malignant acanthosis nigricans is
ventral adenocarcinoma, especially of the stomach. It is individualized
by dark thickened motherly patches, especially in the laps of skin in
the axilla (armpit), groin and back of the neck.
Causes of Acanthosis Nigricans:
The important causes of acanthosis nigricans are given bellow:
1.Heredity disorder, is the main reason of acanthosis nigricans. It is very normal among people of African descent.
2.Acanthosis nigricans is connected with an endocrine disorder or a tumor.
3.Acanthosis nigricans is very normal in dark-skinned individuals, especially those of African American descent.
4.Some
drugs, specially hormones such as human growth hormone or oral
contraceptives ("the pill"), can also provoke acanthosis nigricans.
5.Again,The hypothyroidism may lead to the condition of acanthosis nigricans.
6.People
with cancers of the gastrointestinal or genitourinary tracts or with
lymphoma are more prone to get affected by acanthosis nigricans.
7.Other possible reason of acanthosis nigricans is the obesity, which is frequently found in people with diabetes.
8.Acanthosis
nigricans, may be exhorted by several medications, including nicotinic
acid, insulin, pituitary extract, systemic corticosteroids, and
diethylstilbestrol.
The possible symptoms of acanthosis nigricans are as:-
The
acanthosis nigricans, can be featurised as a dark, velvety skin with
very visible markings and creases appears in the armpits, groin, and
neck.
The dark-brouwn patches are common in the patients of acanthosis nigricans. These dark patches feel velvety and rough.
Itching may be present in the patients with acanthosis nigricans.
AN lesions may also appear on the mucous membranes of the oral cavity, nasal and laryngeal mucosa and oesophagus.
The multiple finger-like growths are common on cutaneous and mucosal surfaces.
Skin tags, may be seen in and around the affected areas.
Treatments of Acanthosis Nigricans:
The effective treatments for acanthosis nigricans includes:-
Niacin (nicotinic acid) is found very efffective in the treatment of acanthosis nigricans.
The antibiotic ointments or creams retinoids are the useful remedies for acanthosis nigricans.
Topical corticosteroid creams, are applied to the defected area of the skin.
Correct hyperinsulinemia through diet and medication, may also help to control the condition.
Acanthosis nigricans, can be avoided by loseing weight of the patient.
Topical retinoids, dermabrasion and laser therapy, are very effective in the treatment of acanthosis nigricans.